Solutions Modeling Dynamics of Life 3ed Adler - Chapter 8.2

8.2.1 In the following situations, find the probability of a result as extreme as or more extreme than the actual result for the given value of the parameter. A coin is flipped five times and comes up heads every time. Does the value p = 0.5 for the probability of heads lie within the 95% confidence limits?
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8.2.2 In the following situations, find the probability of a result as extreme as or more extreme than the actual result for the given value of the parameter. A coin is flipped seven times and comes up heads six out of seven times. Does the value p = 0.5 for the probability of heads lie within the 95% confidence limits?
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8.2.3 In the following situations, find the probability of a result as extreme as or more extreme than the actual result for the given value of the parameter. A person wins the lottery the second time he plays. Does the value q = 0.001 for the probability of success lie within the 99% confidence limits?
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8.2.4 In the following situations, find the probability of a result as extreme as or more extreme than the actual result for the given value of the parameter. A person wins the lottery the fifth time he plays. Does the value q = 0.001 for the probability of success lie within the 99% confidence limits?
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8.2.5 In the following situations, find the probability of a result as extreme as or more extreme than the actual result for the given value of the parameter. Three cosmic rays hit a detector in 1 yr. Does the value λ=10.0 for the rate at which rays hit lie within the 98% confidence limits?
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8.2.6 In the following situations, find the probability of a result as extreme as or more extreme than the actual result for the given value of the parameter. One cosmic ray hits a detector in 1 yr. Does the value λ = 5.0 for the rate at which rays hit lie within the 98% confidence limits?
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8.2.8 Find the exact confidence limits and check if the value for the earlier problem lies within them. Find the 95% confidence limits if a coin is flipped seven times and comes up heads six out of seven times (Exercise 2).
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8.2.8 Find the exact confidence limits and check if the value for the earlier problem lies within them. Find the 95% confidence limits if a coin is flipped seven times and comes up heads six out of seven times (Exercise 2).
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8.2.9 Find the exact confidence limits and check if the value for the earlier problem lies within them. Find the 99% confidence limits if a person wins the lottery the second time he plays (Exercise 3).
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8.2.10 Find the exact confidence limits and check if the value for the earlier problem lies within them. Find the 98% confidence limits if a one cosmic ray hits a detector in 1 yr (Exercise 6).
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8.2.11 Find the approximate 95% confidence limits using the method of support and compare with earlier exercises. A coin is flipped five times and comes up heads every time (Exercise 7).
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8.2.12 Find the approximate 95% confidence limits using the method of support and compare with earlier exercises. A coin is flipped seven times and comes up heads six out of seven times (Exercise 8).
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8.2.13 Find the approximate 95% confidence limits using the method of support and compare with earlier exercises. A person wins the lottery the second time he plays (Exercise 9, but recall that the earlier exercise found 99% confidence limits).
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8.2.14 Find the approximate 95% confidence limits using the method of support and compare with earlier exercises. One cosmic ray hits a detector in 1 yr (Exercise 6, but recall that the earlier exercise found 99% confidence limits).
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8.2.15 Explain how you would use the Monte Carlo method to estimate confidence limits in the following cases. A coin is flipped five times and comes up heads every time, and we wish to find the upper and lower 95% confidence limits.
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8.2.16 Explain how you would use the Monte Carlo method to estimate confidence limits in the following cases. A coin is flipped seven times and comes up heads six out of seven times, and we wish to find upper and lower 95% confidence limits.
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8.2.17 Explain how you would use the Monte Carlo method to estimate confidence limits in the following cases. A person wins the lottery the second time he plays, and we wish to find upper and lower 99% confidence limits.
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8.2.18 Explain how you would use the Monte Carlo method to estimate confidence limits in the following cases. One cosmic ray hits a detector in 1 yr, and we wish to find upper and lower 98% confidence limits.
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8.2.19 Check whether the expected value of p ( p = 1/2 for a fair coin and p = 1/6 for a fair die) lies within the approximate95% confidence limits given by the method of support. Flipping 2 out of 4 heads with a fair coin (as in Section 8.1, Exercise 9).
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8.2.20 Check whether the expected value of p ( p = 1/2 for a fair coin and p = 1/6 for a fair die) lies within the approximate95% confidence limits given by the method of support. Rolling 2 out of 4 sixes with a fair die (as in Section 8.1, Exercise 10).
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8.2.21 Check whether the expected value of p ( p = 1/2 for a fair coin and p = 1/6 for a fair die) lies within the approximate95% confidence limits given by the method of support. Flipping 2 out of 12 heads with a fair coin (as in Section 8.1, Exercise 11).
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8.2.22 Check whether the expected value of p ( p = 1/2 for a fair coin and p = 1/6 for a fair die) lies within the approximate95% confidence limits given by the method of support. Rolling 2 out of 12 sixes with a fair die (as in Section 8.1, Exercise 12).
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8.2.23 Check whether the given value of Λ lies within the approximate 95% confidence limits given by the method of support. Twenty events occur in 1 min with a given value of Λ = 10.0 (as in Section 8.1, Exercise 17).
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8.2.24 Check whether the given value of Λ lies within the approximate 95% confidence limits given by the method of support. Ten high energy cosmic rays hit detector over the course of 1 yr, with a given value of Λ= 8.0 (as in Section 8.1, Exercise 18).
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8.2.25 Use experimentation and Newton’s method to solve the equations for the approximate confidence limits with the method of support. The confidence limits if 20 out of 100 individuals are measured with a particular allele (Example 8.2.13).
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8.2.26 Use experimentation and Newton’s method to solve the equations for the approximate confidence limits with the method of support. The confidence limits if 23 seeds are found in 1 ... (Example 8.2.14).
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8.2.27 prove that the support takes on its maximum where the likelihood does. Using the likelihood function in Section 8.1, Exercise 9.
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8.2.28 prove that the support takes on its maximum where the likelihood does. Using the likelihood function in Section 8.1, Exercise 17.Reference Section 8.1, Exercise 17 Find the likelihood as a function of the Poisson parameter Λ, find the maximum likelihood estimator, and evaluate the likelihood at the maximum and at the other given value of Λ. Twenty events occur in 1 min. Compare the likelihood with the maximum likelihood estimator of Λ with the likelihood if Λ= 10.0.
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8.2.29 prove that the support takes on its maximum where the likelihood does. Using the likelihood function in Section 8.1, Exercise 19. Section 8.1, Exercise 19.Find the likelihood as a function of the Poisson parameter Λ, find the maximum likelihood estimator, and evaluate the likelihood at the maximum and at the other given value of Λ. The number of events that occur are counted for 3 min. Twenty events occur the first minute, 16 events occur the second minute, and 21 events occur the third minute. Compare the likelihood with the maximum likelihood estimator of Λ with the likelihood if Λ= 20.0.
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8.2.30 prove that the support takes on its maximum where the likelihood does. For a general likelihood function.
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8.2.31 Consider a tiny data set where one out of two people is found with an allele. Find the exact 95% confidence limits.
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8.2.32 Consider a tiny data set where one out of two people is found with an allele. Find the exact 99% confidence limits.
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8.2.33 Consider a tiny data set where one out of two people is found with an allele. How would you use the Monte Carlo method to estimate the 99% confidence limits?
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8.2.34 Consider a tiny data set where one out of two people is found with an allele. Use the method of support to estimate 95% confidence limits and compare your results with Exercise 31.
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8.2.35 Consider a data set where three out of three people are found with an allele. Find the exact 95% confidence limits.
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8.2.36 Consider a data set where three out of three people are found with an allele. Find the exact 99% confidence limits.
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8.2.37 Consider a data set where three out of three people are found with an allele. Why is the upper confidence limit strange?
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8.2.38 Consider a data set where three out of three people are found with an allele. Use the method of support to estimate 95% confidence limits and compare your results with Exercise 35.
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8.2.39 A person places an advertisement to sell his car in the newspaper and settles down to await calls, which he expects will arrive with an exponential distribution. The first call arrives in 20 min. Find the maximum likelihood estimator of the rate.
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8.2.40 A person places an advertisement to sell his car in the newspaper and settles down to await calls, which he expects will arrive with an exponential distribution. The first call arrives in 20 min. Find the 95% confidence limits.
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8.2.41 A person places an advertisement to sell his car in the newspaper and settles down to await calls, which he expects will arrive with an exponential distribution. The first call arrives in 20 min. Find the 98% confidence limits.
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8.2.42 A person places an advertisement to sell his car in the newspaper and settles down to await calls, which he expects will arrive with an exponential distribution. The first call arrives in 20 min. How many calls might he expect to miss if he went out for a 2-h hike?
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8.2.43 14 mutations are counted in one million base pairs. Write the equations for the 95% confidence limits, and solve them numerically if you have a computer.
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8.2.44 Recall the couple that has seven boys before having a girl (Section 8.1, Exercise 33). Find 95% confidence limits around the maximum likelihood estimate of q. How do you interpret these results?
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8.2.45 Recall the couple that has seven boys before having a girl (Section 8.1, Exercise 33). Find 95% confidence limits around the maximum likelihood estimate of q. How do you interpret these results?
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8.2.46 Recall the couple that has seven boys before having a girl (Section 8.1, Exercise 33). Find 99% confidence limits around the maximum likelihood estimate of q. How do you interpret these results?
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8.2.48 Consider again the data in Section 8.1, Exercise 50. Use the method of support to find approximate 95% confidence limits around your estimated value. Do they include the true value x = 3.0? Reference Section 8.1, Exercise 50. Cells are placed for 1 min in an environment where they are hit by X-rays, some of which are damaging. Cells not hit by the damaging rays are healthy, those hit exactly once are damaged, and those hit more than once are dead. By measuring the states of a number of cells, we wish to infer the rate at which cells are hit by damaging rays. Let x denote the unknown parameter of the Poisson distribution. Use the formula for the Poisson distribution to compute the probabilities ...of more than one hit in 1 min as functions of x.
a. Suppose the true value of x is 3.0. Plot the histogram. b. Simulate 50 cells, and count how many you have of each type. (To keep things interesting, keep sampling until you get at least one cell of each type.)
c. Compare the results of your simulation with the idealized histogram.
d. Now pretend that x is unknown. We can use the method of maximum likelihood to analyze our data. Find the likelihood function L of these data (it is the product of the likelihoods for each of the 50 cells) as a function of the unknown parameter y, and let S be the natural log of L. Plot S(y) over a reasonable range.
e. Find the maximum of S and mark it on your graph.
f. Find the S(x) for x = ..., x = 2, x = 4, and the “truth” x = 3, and indicate each on your graph.
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8.2.48 Consider again the data in Section 8.1, Exercise 50. Use the method of support to find approximate 95% confidence limits around your estimated value. Do they include the true value x = 3.0? Reference Section 8.1, Exercise 50. Cells are placed for 1 min in an environment where they are hit by X-rays, some of which are damaging. Cells not hit by the damaging rays are healthy, those hit exactly once are damaged, and those hit more than once are dead. By measuring the states of a number of cells, we wish to infer the rate at which cells are hit by damaging rays. Let x denote the unknown parameter of the Poisson distribution. Use the formula for the Poisson distribution to compute the probabilities ...of more than one hit in 1 min as functions of x.
a. Suppose the true value of x is 3.0. Plot the histogram. b. Simulate 50 cells, and count how many you have of each type. (To keep things interesting, keep sampling until you get at least one cell of each type.)
c. Compare the results of your simulation with the idealized histogram.
d. Now pretend that x is unknown. We can use the method of maximum likelihood to analyze our data. Find the likelihood function L of these data (it is the product of the likelihoods for each of the 50 cells) as a function of the unknown parameter y, and let S be the natural log of L. Plot S(y) over a reasonable range.
e. Find the maximum of S and mark it on your graph.
f. Find the S(x) for x = ..., x = 2, x = 4, and the “truth” x = 3, and indicate each on your graph.
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8.2.49 Use the Monte Carlo method to estimate the 95% confidence limits in Exercise 18. How close are your results to those obtained with the other methods?
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